Issue Description

Spider-Man attempts to find the ISO-36 serum that may provide a cure for Aunt May. But from whose hands must he acquire this unique formula? Peter must make some difficult choices to save the ones he loves.

We see Spider-Man as we left him last issue, His Aunt May is dying in the hospital and the only thing that can save her is the serum known as ISO-36, It is near him but he is in engulfed by water and heavy machinery in the Master Planner's underwater base. He tries to pick it up but he is too exhausted from his fight with Dr. Octopus. There are cracks in the ceiling that are getting bigger and bigger. In any moment the whole river above him can drop below. After struggling for a long while and almost giving up, Spidey reminds himself of his responsibility to Aunt May, that her life depends on him getting the sample to Dr. Connors. With that in mind, Spider-Man uses every last ounce of strength and his iron will to push the weight off and away from him. With his leg badly injured, Spider-Man grabs the serum containing the isotope ISO-36 just as the roof collapses above him creating a huge amount of water that violently sweeps him through a tunnel with henchmen waiting for him. After a beating from the henchmen Spidey knocks them all out without being aware of it. With no time to think about where Doctor Octopus has went, Spider-Man delivers the ISO-36 to Doctor Connors just in time. After long hours and a positive test with May's stolen blood sample, the serum is proven to be a success. He returns to the scene with the out-cold henchmen and snaps a few pictures of them and then Calls Daily Bugle so that Fredrick Foswell can report the story. Back at the Bugle, Peter is there all bruised up and Betty Brant wonders what happened to him. Peter says it was part of his job of getting new photos for Jameson. Peter returns to the hospital to check on Aunt May's condition and the final series of test are in. Good news is reported that the serum is a success. For everything Peter loses in this story, he achieves what mattered the most.

The Amazing Spider-Man (1963)

Publisher

Marvel

Volume Description

After the success of Amazing Fantasy #15 (Aug. 1962) a few months later the same creative team came back to start an ongoing series focusing on the character the two of them created.

The book's run continued until issue number 441 (Nov. 1998) when Marvel relaunched the title as Amazing Spider-Man Volume 2 with a new number 1 in January 1999. After issue #30 (#471) Marvel used a dual numbering system, yet the indicia still stated The Amazing Spider-Man Vol. 2. On the title's 40th anniversary the numbering was reverted to go from issue 58 to issue 500 (Dec. 2003) as The Amazing Spider-Man Vol. 1.

This volume ends with #700 and is picked up by the Marvel Now! revolution volume Superior Spider-Man.

Collected EditionsMarvel Masterworks: The Amazing Spider-Man Vol. 1 (#1-10)Marvel Masterworks: The Amazing Spider-Man Vol. 2 (#11-19)Marvel Masterworks: The Amazing Spider-Man Vol. 3 (#20-30)Marvel Masterworks: The Amazing Spider-Man Vol. 4 (#31-40)Marvel Masterworks: The Amazing Spider-Man Vol. 5 (#41-50)Marvel Masterworks: The Amazing Spider-Man Vol. 6 (#51-61)Marvel Masterworks: The Amazing Spider-Man Vol. 7 (#62-67)Marvel Masterworks: The Amazing Spider-Man Vol. 8 (#68-77)Marvel Masterworks: The Amazing Spider-Man Vol. 9 (#78-87)Marvel Masterworks: The Amazing Spider-Man Vol. 10 (#88-99)Marvel Masterworks: The Amazing Spider-Man Vol. 11 (#100-109)Marvel Masterworks: The Amazing Spider-Man Vol. 12 (#110-120)Marvel Masterworks: The Amazing Spider-Man Vol. 13 (#121-131)Marvel Masterworks: The Amazing Spider-Man Vol. 14 (#132-142)Marvel Masterworks: The Amazing Spider-Man Vol. 15 (#143-155)Marvel Masterworks: The Amazing Spider-Man Vol. 16 (#156-168 and Annual #10)Spider-Man vs. Black Cat (#194-195, 204-205, 226-227.)Spider-Man: Nothing Can Stop the Juggernaut (#224-230)Birth of Venom (#252-259, #298-300)The Amazing Spider-Man: The Complete Alien Costume Saga Book 1 (#252-258)The Amazing Spider-Man: The Complete Alien Costume Saga Book 2 (#259-263)Kraven's Last Hunt (#293-294)The Amazing Spider-Man: Life in the Mad Dog Ward (#295)Amazing Spider-Man by David Michelinie & Todd McFarlane (#296-329)Sinister Six (#334-339)Powerless (#341-343)Amazing Spider-Man Epic Collection: Round Robin (#351-360)Round Robin (#353-358)Maximum Carnage (#378-380)

Collection of sequentially numbered trades, Amazing Spider-Man.

Spider-Man: Mark of the Tarantula (#231-237)Coming Home (#471-476)Revelations (#477-480)Until the Stars Turn Cold (#481-486)Life and Death of Spiders (#487-491)Unintended Consequences (#492-497)Happy Birthday (#498-502)The Book of Ezekiel (#503-508)Sins Past (#509-514)Skin Deep (#515-518)New Avengers (#519-524)

Individual trades with their own volumes because of sub-titles.

The Amazing Spider-Man Epic Collection: Great Power (#1-17)Punisher vs. the Marvel Universe (#161-162)The Amazing Spider-Man Epic Collection: Ghosts of the Past (#259-272)The Amazing Spider-Man Epic Collection: Return of the Sinister Six (#334-350)Spider-Man: The Gathering of Five (#440-441)The Other (#525-528)The Road to Civil War (#529-531)Civil War (#532-538)Back in Black (#539-543)One More Day (#544-545)Brand New Day Vol 1 (#546-551)Brand New Day Vol 2 (#552-558)Brand New Day Vol 3 (#559-564)Kraven's First Hunt (#565-567)New Ways to Die (#568-573)Crime and Punisher (#574-577)Death and Dating (#578-583)Election Day (#584-588)24/7 (#589-594)American Son (#595-599)Died in Your Arms Tonight (#600-601)Red-Headed Stranger (#602-605)Return of The Black Cat (#606-611)The Gauntlet, Vol 1 (#612-616)The Gauntlet, Vol 2 (#617-621)The Gauntlet, Vol 3 (#622-625)The Gauntlet, Vol 4 (#626-629)The Gauntlet, Vol 5 (#630-633)The Grim Hunt (#634-637)One Moment in Time (#638-641)Origin of the Species (#642-647)Big Time (#648-651)Matters of Life and Death (#652-657)The Fantastic Spider-Man (#658-662)Big Time Ultimate Collection (#648-662)The Return of Anti-Venom (#663-665)Amazing Spider-Man: Big Time - The Complete Collection vol. 2 (#663-676)Spider-Island (#666-673)Flying Blind (#674-677)Amazing Spider-Man: Big Time - The Complete Collection vol. 3 (#677-687 and 679.1)Trouble on the Horizon (#678-681, #679.1)Ends of the Earth (#682-687)No Turning Back (#688-691)Amazing Spider-Man: Big Time - The Complete Collection vol. 4 (#688-697)Danger Zone (#692-697)Dying Wish (#698-700)Amazing Spider-Man: Peter Parker The One And Only (#700.1-700.5)

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